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Journal article

Vitamin D receptor gene methylation is associated with ethnicity, tuberculosis, and TaqI polymorphism.

Abstract:

The Vitamin D receptor (VDR) gene encodes a transcription factor which, on activation by vitamin D, modulates diverse biologic processes, including calcium homeostasis and immune function. Genetic variation involving VDR shows striking differences in allele frequency between populations and has been associated with disease susceptibility, including tuberculosis and autoimmunity, although results have often been conflicting. We hypothesized that methylation of VDR may be population specific an...

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Publication status:
Published

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Journal:
Human immunology
Volume:
72
Issue:
3
Pages:
262-268
Publication date:
2011-03-05
DOI:
EISSN:
1879-1166
ISSN:
0198-8859
URN:
uuid:1e518e89-054b-406b-919c-1cd54d35a98d
Source identifiers:
115869
Local pid:
pubs:115869

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