Journal article
Hematopoietic stem cell emergence in the conceptus and the role of Runx1.
- Abstract:
-
Hematopoietic stem cells (HSCs) are functionally defined as cells that upon transplantation into irradiated or otherwise immunocompromised adult organisms provide long-term reconstitution of the entire hematopoietic system. They emerge in the vertebrate conceptus around midgestation. Genetic studies have identified a number of transcription factors and signaling molecules that act at the onset of hematopoiesis, and have begun to delineate the molecular mechanisms underlying the formation of H...
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- Publication status:
- Published
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- Publisher copy:
- 10.1387/ijdb.103106gs
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Authors
Bibliographic Details
- Journal:
- International journal of developmental biology
- Volume:
- 54
- Issue:
- 6-7
- Pages:
- 1151-1163
- Publication date:
- 2010-01-01
- DOI:
- EISSN:
-
1696-3547
- ISSN:
-
0214-6282
- Source identifiers:
-
255081
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:255081
- UUID:
-
uuid:1e4cb1d9-9052-48e9-9196-8c25e4c7e580
- Local pid:
- pubs:255081
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2010
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