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Dopamine signaling in dorsal versus ventral striatum: the dynamic role of cholinergic interneurons.

Abstract:

Mesostriatal dopaminergic neurons and striatal cholinergic interneurons participate in signaling the motivational significance of environmental stimuli and regulate striatal plasticity. Dopamine (DA) and acetylcholine (ACh) have potent interactions within the striatum at multiple levels that include presynaptic regulation of neurotransmitter release and postsynaptic effects in target cells (including ACh neurons). These interactions may be highly variable given the dynamic changes in the firi...

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Publisher copy:
10.3389/fnsys.2011.00011

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Journal:
Frontiers in systems neuroscience
Volume:
5
Pages:
11
Publication date:
2011
DOI:
EISSN:
1662-5137
ISSN:
1662-5137
URN:
uuid:1e462449-070a-448c-ab11-ef1cbb88b28e
Source identifiers:
127180
Local pid:
pubs:127180

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