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Oocyte activation and fertilisation: crucial contributors from the sperm and oocyte

Abstract:

This chapter intends to summarise the importance of sperm- and oocyte-derived factors in the processes of sperm-oocyte binding and oocyte activation. First, we describe the initial interaction between sperm and the zona pellucida, with particular regard to acrosome exocytosis. We then describe how sperm and oocyte membranes fuse, with special reference to the discovery of the sperm protein IZUMO1 and its interaction with the oocyte membrane receptor JUNO. We then focus specifically upon o...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/978-3-319-44820-6_8

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Obstetrics & Gynaecology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Obstetrics & Gynaecology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Obstetrics & Gynaecology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Obstetrics & Gynaecology
Role:
Author
EU FP7 People Programme More from this funder
Ministry of Education, Brunei Darussalam More from this funder
Universiti Brunei Darussalam More from this funder
Publisher:
Springer, Cham Publisher's website
Pages:
213-239
Series:
Results and Problems in Cell Differentiation
Host title:
Signaling-Mediated Control of Cell Division
Publication date:
2017-03-01
Acceptance date:
2017-03-01
DOI:
EISBN:
9783319448206
ISSN:
0080-1844
Pubs id:
pubs:817890
URN:
uri:1e40b5bd-738d-44eb-9a56-6a860c9a38da
UUID:
uuid:1e40b5bd-738d-44eb-9a56-6a860c9a38da
Local pid:
pubs:817890
ISBN:
9783319448190

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