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A structural equation modelling approach to explore the role of B vitamins and immune markers in lung cancer risk.

Abstract:

The one-carbon metabolism (OCM) is considered key in maintaining DNA integrity and regulating gene expression, and may be involved in the process of carcinogenesis. Several B-vitamins and amino acids have been implicated in lung cancer risk, via the OCM directly as well as immune system activation. However it is unclear whether these factors act independently or through complex mechanisms. The current study applies structural equations modelling (SEM) to further disentangle the mechanisms inv...

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Publisher copy:
10.1007/s10654-013-9793-z

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Journal:
European journal of epidemiology
Volume:
28
Issue:
8
Pages:
677-688
Publication date:
2013-08-05
DOI:
EISSN:
1573-7284
ISSN:
0393-2990
URN:
uuid:1e3ff1c0-5dfb-4315-bb7c-812eb0545514
Source identifiers:
432601
Local pid:
pubs:432601

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