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Cortisol secretion and rate of bone loss in a population-based cohort of elderly men and women.

Abstract:

Although excessive glucocorticoids are a well-recognized cause of osteoporosis, little is known about the role of endogenous glucocorticoids in determining skeletal mass. We have performed a detailed study of the hypothalamic-pituitary-adrenal (HPA) axis to explore the relationships between cortisol secretion and adult bone mass in 151 healthy men and 96 healthy women aged 61 to 73 years. At baseline and 4-year follow-up, bone mineral density (BMD) was measured by dual energy X-ray absorptiom...

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Publication status:
Published

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Publisher copy:
10.1007/s00223-004-0270-2

Authors


Reynolds, RM More by this author
Dennison, EM More by this author
Walker, BR More by this author
Syddall, HE More by this author
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Journal:
Calcified tissue international
Volume:
77
Issue:
3
Pages:
134-138
Publication date:
2005-09-05
DOI:
EISSN:
1432-0827
ISSN:
0171-967X
URN:
uuid:1e2a00eb-f3c2-4df9-beb4-476dfe9a8449
Source identifiers:
125816
Local pid:
pubs:125816

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