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HIV-1 RNA dimerization: It takes two to tango.

Abstract:

Each viral particle of HIV-1, the infectious agent of AIDS, contains two copies of the full-length viral genomic RNA. Encapsidating two copies of genomic RNA is one of the characteristics of the retrovirus family. The two RNA molecules are both positive-sense and often identical; furthermore, each RNA encodes the full complement of genetic information required for viral replication. The two strands of RNA are intricately entwined within the core of the mature infectious virus as a ribonuclear...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
AIDS reviews
Volume:
11
Issue:
2
Pages:
91-102
Publication date:
2009-01-01
EISSN:
1698-6997
ISSN:
1139-6121
Source identifiers:
228615
Language:
English
Keywords:
Pubs id:
pubs:228615
UUID:
uuid:1e23e168-cc4b-4afb-a378-283e13b7bcdb
Local pid:
pubs:228615
Deposit date:
2012-12-19

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