- Abstract:
-
Acetylcholine receptor (AChR) antibodies are present in around 85% of patients with myasthenia gravis (MG) as measured by the conventional radioimmunoprecipitation assay. Antibodies that block the fetal form of the AChR are occasionally present in mothers who develop MG after pregnancy, especially in those whose babies are born with arthrogryposis multiplex congenita. The antibodies cross the placenta and block neuromuscular transmission, leading to joint deformities and often stillbirth. In ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1196/annals.1254.036
-
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- Journal:
- Annals of the New York Academy of Sciences
- Volume:
- 998
- Issue:
- 1
- Pages:
- 324-335
- Publication date:
- 2003-09-05
- DOI:
- EISSN:
-
1749-6632
- ISSN:
-
0077-8923
- URN:
-
uuid:1e1607ec-418b-4234-916c-4127f883be95
- Source identifiers:
-
241141
- Local pid:
- pubs:241141
- Language:
- English
- Keywords:
- Copyright date:
- 2003
Journal article
Antibodies in myasthenia gravis and related disorders.
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