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Morphometric immunochemical analysis of neurons in the nucleus basalis of Meynert in Alzheimer's disease.

Abstract:

In Alzheimer's disease there is a reported loss of large cells in the cholinergic nucleus basalis of Meynert. It has been suggested, however, that there may be neurons in the nucleus basalis in Alzheimer's disease which are atrophied and therefore difficult to distinguish from neuroglia by size. This has important therapeutic implications and we have attempted to clarify the situation using a neuron-specific antiserum directed against neuron-specific enolase (NSE). Sections of nucleus basalis...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Brain research More from this journal
Volume:
454
Issue:
1-2
Pages:
275-281
Publication date:
1988-06-01
DOI:
EISSN:
1872-6240
ISSN:
0006-8993
Language:
English
Keywords:
Pubs id:
pubs:35338
UUID:
uuid:1e0c78ea-c43d-485c-a68c-20fc3d244fff
Local pid:
pubs:35338
Source identifiers:
35338
Deposit date:
2012-12-19

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