Journal article
Oxidation Resistance 1 Modulates Glycolytic Pathways in the Cerebellum via an Interaction with Glucose-6-Phosphate Isomerase
- Abstract:
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Glucose metabolism is essential for the brain: it not only provides the required energy for cellular function and communication but also participates in balancing the levels of oxidative stress in neurons. Defects in glucose metabolism have been described in neurodegenerative disease; however, it remains unclear how this fundamental process contributes to neuronal cell death in these disorders. Here, we investigated the molecular mechanisms driving the selective neurodegeneration in an ataxic...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 6.9MB)
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- Publisher copy:
- 10.1007/s12035-018-1174-x
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Authors
Funding
Medical Research Council
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Biotechnology and Biological Sciences Research Council
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Bibliographic Details
- Publisher:
- Springer Publisher's website
- Journal:
- Molecular Neurobiology Journal website
- Publication date:
- 2018-06-15
- Acceptance date:
- 2018-06-01
- DOI:
- EISSN:
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1559-1182
- ISSN:
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0893-7648
- Pmid:
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29905912
- Source identifiers:
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858623
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:858623
- UUID:
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uuid:1e0a7b6a-25aa-48c7-8e2f-89ca08fe97ad
- Local pid:
- pubs:858623
- Deposit date:
- 2018-06-27
Terms of use
- Copyright holder:
- Finelli et al
- Copyright date:
- 2018
- Notes:
- © The Author(s) 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
- Licence:
- CC Attribution (CC BY)
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