Monitoring cholesterol levels: measurement error or true change?
BACKGROUND: Cholesterol level monitoring is a common clinical activity, but the optimal monitoring interval is unknown and practice varies. OBJECTIVE: To estimate, in patients receiving cholesterol-lowering medication, the variation in initial response to treatment, the long-term drift from initial response, and the detectability of long-term changes in on-treatment cholesterol level ("signal") given short-term, within-person variation ("noise"). DESIGN: Analysis of cholesterol measurement d...Expand abstract
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