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Monitoring cholesterol levels: measurement error or true change?

Abstract:

BACKGROUND: Cholesterol level monitoring is a common clinical activity, but the optimal monitoring interval is unknown and practice varies. OBJECTIVE: To estimate, in patients receiving cholesterol-lowering medication, the variation in initial response to treatment, the long-term drift from initial response, and the detectability of long-term changes in on-treatment cholesterol level ("signal") given short-term, within-person variation ("noise"). DESIGN: Analysis of cholesterol measurement d...

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Authors


Glasziou, PP More by this author
Heritier, S More by this author
Journal:
Annals of internal medicine
Volume:
148
Issue:
9
Pages:
656-661
Publication date:
2008-05-05
DOI:
EISSN:
1539-3704
ISSN:
0003-4819
URN:
uuid:1dff2796-0b35-435c-9f97-a96bf6e11d27
Source identifiers:
215807
Local pid:
pubs:215807

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