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Journal article

Evolutionary origin of the staphylococcal cassette chromosome mec (SCCmec).

Abstract:

Several lines of evidence indicate that the most primitive staphylococcal species, those of the Staphylococcus sciuri group, were involved in the first stages of evolution of the staphylococcal cassette chromosome mec (SCCmec), the genetic element carrying the β-lactam resistance gene mecA However, many steps are still missing from this evolutionary history. In particular, it is not known how mecA was incorporated into the mobile element SCC prior to dissemination among Staphylococcus aureus ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1128/AAC.02302-16

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
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Name:
Wellcome Trust
Grant:
090532/Z/09/Z
More from this funder
Name:
Medical Research Council
Grant:
G0800778
More from this funder
Name:
U.S. Public Health Service
More from this funder
Name:
Molecular Structural and Cellular Microbiology Unit
More from this funder
Name:
European Society of Clinical Microbiology and Infectious Diseases
Publisher:
American Society for Microbiology
Journal:
Antimicrobial Agents and Chemotherapy More from this journal
Volume:
61
Issue:
6
Pages:
e02302-16
Publication date:
2017-04-01
Acceptance date:
2017-03-10
DOI:
EISSN:
1098-6596
ISSN:
0066-4804
Language:
English
Keywords:
Pubs id:
pubs:688837
UUID:
uuid:1dde013f-b0b0-40eb-a4a0-8b5cf93ebb21
Local pid:
pubs:688837
Source identifiers:
688837
Deposit date:
2017-08-11

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