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Localisation and semi-quantitative measurement of lipocortin 1 in rat anterior pituitary cells by fluorescence-activated cell analysis/sorting and electron microscopy.

Abstract:

Lipocortin 1 (LC1, also called annexin 1), a Ca2(+)- and phospholipid-binding protein, is an important mediator of glucocorticoid action in the anterior pituitary gland. Previous studies based on immunoprecipitation and Western blot analysis suggest that LC1 is found intracellularly both in the cytoplasm and in association with membranes and also on the cell surface where it attaches to the membrane by a Ca2(+)-dependent mechanism. However, as yet it is unclear which anterior pituitary cell t...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Journal of neuroendocrinology
Volume:
11
Issue:
9
Pages:
707-714
Publication date:
1999-09-01
DOI:
EISSN:
1365-2826
ISSN:
0953-8194
Source identifiers:
114463
Language:
English
Keywords:
Pubs id:
pubs:114463
UUID:
uuid:1dd9a349-483b-4c1d-bdfe-da55d70ee65e
Local pid:
pubs:114463
Deposit date:
2012-12-19

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