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Journal article

The effect of tumour necrosis factor-alpha (TNF-alpha) muteins on human neutrophils in vitro.

Abstract:

Tumour necrosis factor-alpha (TNF-alpha) has been implicated as an important inflammatory mediator. In vitro, TNF-alpha is reported to activate human polymorphonuclear neutrophils (PMN), inducing responses such as phagocytic activity, degranulation and oxidative metabolism. Biological responses to TNF-alpha are initiated by its binding to specific cell surface receptors, and various studies have shown that the major TNF receptor species on PMN is the 75 kDa receptor. To verify the suggestion ...

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Publication status:
Published

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Publisher copy:
10.1155/s0962935193000055

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Journal:
Mediators of inflammation
Volume:
2
Issue:
1
Pages:
41-48
Publication date:
1993-01-01
DOI:
EISSN:
1466-1861
ISSN:
0962-9351
URN:
uuid:1dc0cbcb-0efd-4578-9dc6-9f953a4a1fec
Source identifiers:
481917
Local pid:
pubs:481917

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