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Thesis

Intercellular signalling in the prostate cancer tumour microenvironment: implications for disease progression

Abstract:

Advanced prostate cancer (PCa) is incurable and presents a significant clinical challenge. Once metastasised, crosstalk between PCa cells and other cells within the tumour microenvironment (TME) is critical for tumour growth. Hence, disrupting tumour-stroma interactions has been highlighted as a therapeutic strategy to combat disease progression. However, the intercellular signalling mechanisms underpinning PCa cell growth within the TME are still incompletely understood. Enhanced signalli...

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Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author

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Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
UUID:
uuid:1da54044-93e7-4abd-b313-435148067af2
Deposit date:
2019-07-04

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