Intercellular signalling in the prostate cancer tumour microenvironment: implications for disease progression

Thesis

Advanced prostate cancer (PCa) is incurable and presents a significant clinical challenge. Once metastasised, crosstalk between PCa cells and other cells within the tumour microenvironment (TME) is critical for tumour growth. Hence, disrupting tumour-stroma interactions has been highlighted as a therapeutic strategy to combat disease progression. However, the intercellular signalling mechanisms underpinning PCa cell growth within the TME are still incompletely understood. Enhanced signalli...

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Authors: McCormick, K

• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English