Evolving mechanical properties of a model of abdominal aortic aneurysm.

Journal article

The novel three-dimensional (3D) mathematical model for the development of abdominal aortic aneurysm (AAA) of Watton et al. Biomech Model Mechanobiol 3(2): 98-113, (2004) describes how changes in the micro-structure of the arterial wall lead to the development of AAA, during which collagen remodels to compensate for loss of elastin. In this paper, we examine the influence of several of the model's material and remodelling parameters on growth rates of the AAA and compare with clinical data. F...

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Authors: Watton, P; Hill, N

• Publication status: Published
• Journal: Biomechanics and modeling in mechanobiology
• Volume: 8
• Issue: 1
• Pages: 25-42
• Publication date: 2009-02-01
• DOI: 10.1007/s10237-007-0115-9
• EISSN: 1617-7940
• ISSN: 1617-7959
• Language: English
• Keywords: Computer Simulation; Animals; Viscosity; Shear Strength; Aorta, Abdominal; Humans; Models, Cardiovascular; Blood Pressure; Blood Flow Velocity; Stress, Mechanical; Aortic Aneurysm, Abdominal; Elastic Modulus