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Developing a blood cell-based diagnostic test for myalgic encephalomyelitis/chronic fatigue syndrome using peripheral blood mononuclear cells

Abstract:

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by debilitating fatigue that profoundly impacts patients' lives. Diagnosis of ME/CFS remains challenging, with most patients relying on self-report, questionnaires, and subjective measures to receive a diagnosis, and many never receiving a clear diagnosis at all. In this study, a single-cell Raman platform and artificial intelligence are utilized to analyze blood cells from 98 human subjects, including 61 ME/CFS pati...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/advs.202302146

Authors


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Role:
Author
ORCID:
0000-0002-1285-9408
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Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
Oxford college:
Green Templeton College
Role:
Author
ORCID:
0000-0001-6065-0935
Publisher:
Wiley
Journal:
Advanced Science More from this journal
Volume:
10
Issue:
30
Article number:
e2302146
Publication date:
2023-08-31
Acceptance date:
2023-07-12
DOI:
EISSN:
2198-3844
Pmid:
37653608
Language:
English
Keywords:
Pubs id:
1518377
Local pid:
pubs:1518377
Deposit date:
2023-11-11

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