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Journal article

The role of immune correlates of protection on the pathway to licensure, policy decision and use of group B Streptococcus vaccines for maternal immunization: considerations from World Health Organization consultations

Abstract:

The development of a group B Streptococcus (GBS) vaccine for maternal immunization constitutes a global public health priority, to prevent GBS-associated early life invasive disease, stillbirth, premature birth, maternal sepsis, adverse neurodevelopmental consequences, and to reduce perinatal antibiotic use. Sample size requirements for the conduct of a randomized placebo-controlled trial to assess vaccine efficacy against the most relevant clinical endpoints, under conditions of appropriate ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1016/j.vaccine.2019.04.039

Authors


Publisher:
Elsevier Publisher's website
Journal:
Vaccine Journal website
Volume:
37
Issue:
24
Pages:
3190-3198
Publication date:
2019-04-25
Acceptance date:
2019-04-11
DOI:
EISSN:
1873-2518
ISSN:
0264-410X
Keywords:
Pubs id:
pubs:995523
UUID:
uuid:1d92ec32-02fc-4223-9d1d-f9541521ae72
Local pid:
pubs:995523
Source identifiers:
995523
Deposit date:
2019-05-05

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