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Tumour angiogenesis: the gap between theory and experiments.

Abstract:

A common experimental technique for viewing in vivo angiogenesis utilises tumours implanted into a test animal cornea. The cornea is avascular but the tumour promotes vascularisation from the limbus and the new blood vessels can be readily observed through the transparent cornea. Many of the early mathematical models for tumour angiogenesis used this scenario as their experimental template and as such assumed that there is a large gap, of the order of 2mm, between the tumour and neighbouring ...

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Publication status:
Published

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Publisher copy:
10.1016/j.jtbi.2011.01.012

Authors


Schofield, JW More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
Gatenby, RA More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
Journal:
Journal of theoretical biology
Volume:
274
Issue:
1
Pages:
97-102
Publication date:
2011-04-05
DOI:
EISSN:
1095-8541
ISSN:
0022-5193
URN:
uuid:1d861bd9-3712-4a94-83f5-a5390b4cc61c
Source identifiers:
115701
Local pid:
pubs:115701

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