Journal article
Increased interleukin-26 in the peripheral joints of patients with axial spondyloarthritis and psoriatic arthritis, co-localizing with CD68-positive synoviocytes
- Abstract:
-
Objectives: IL26 levels are elevated in the blood and synovial fluid of patients with inflammatory arthritis. IL26 can be produced by Th17 cells and locally within joints by tissue-resident cells. IL26 induces osteoblast mineralization in vitro. As osteoproliferation and Th17 cells are important factors in the pathogenesis of axial spondyloarthritis (axSpA), we aimed to clarify the cellular sources of IL26 in spondyloarthritis. Methods: Serum, peripheral blood mononuclear cells (n = 15–35) an...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Version of record, pdf, 8.1MB, Terms of use)
-
(Preview, Version of record, pdf, 528.8KB, Terms of use)
-
- Publisher copy:
- 10.3389/fimmu.2024.1355824
Authors
Bibliographic Details
- Publisher:
- Frontiers Media
- Journal:
- Frontiers in Immunology More from this journal
- Volume:
- 15
- Article number:
- 1355824
- Publication date:
- 2024-05-10
- Acceptance date:
- 2024-04-01
- DOI:
- EISSN:
-
1664-3224
Item Description
- Language:
-
English
- Keywords:
- Source identifiers:
-
1991500
- Deposit date:
-
2024-07-20
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record