Journal article icon

Journal article

Increased interleukin-26 in the peripheral joints of patients with axial spondyloarthritis and psoriatic arthritis, co-localizing with CD68-positive synoviocytes

Abstract:

Objectives: IL26 levels are elevated in the blood and synovial fluid of patients with inflammatory arthritis. IL26 can be produced by Th17 cells and locally within joints by tissue-resident cells. IL26 induces osteoblast mineralization in vitro. As osteoproliferation and Th17 cells are important factors in the pathogenesis of axial spondyloarthritis (axSpA), we aimed to clarify the cellular sources of IL26 in spondyloarthritis. Methods: Serum, peripheral blood mononuclear cells (n = 15–35) an...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.3389/fimmu.2024.1355824

Authors


Publisher:
Frontiers Media
Journal:
Frontiers in Immunology More from this journal
Volume:
15
Article number:
1355824
Publication date:
2024-05-10
Acceptance date:
2024-04-01
DOI:
EISSN:
1664-3224
Language:
English
Keywords:
Source identifiers:
1991500
Deposit date:
2024-07-20

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP