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Transcriptome dynamics of the suprachiasmatic nucleus and associations with psychiatric disease

Abstract:

The mammalian suprachiasmatic nucleus (SCN) drives daily rhythmic behaviour and physiology, yet a comprehensive understanding of its coordinated transcriptional programmes is lacking. Furthermore, there has been a long-standing association between circadian disruption and psychiatric disease, whose mechanism underpinnings are unknown. To analyse in detail the circadian transcriptome of the mammalian SCN and its variation in psychiatric disease, whole transcriptome sequencing (RNA-seq) of t...

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Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author

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Supervisor
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Supervisor
Medical Research Council More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:1d652e3b-d5ee-462b-9e3c-e39ed1470efd
Deposit date:
2017-07-17

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