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Discrepancies between BOLD and flow dynamics in primary and supplementary motor areas: application of the balloon model to the interpretation of BOLD transients.

Abstract:

The blood-oxygen-level-dependent (BOLD) signal measured in the brain with functional magnetic resonance imaging (fMRI) during an activation experiment often exhibits pronounced transients at the beginning and end of the stimulus. Such transients could be a reflection of transients in the underlying neural activity, or they could result from transients in cerebral blood flow (CBF), cerebral metabolic rate of oxygen (CMRO2), or cerebral blood volume (CBV). These transients were investigated usi...

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Journal:
NeuroImage More from this journal
Volume:
21
Issue:
1
Pages:
144-153
Publication date:
2004-01-01
DOI:
EISSN:
1095-9572
ISSN:
1053-8119

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