Genotype imputation is potentially a zero-cost method for bridging gaps in coverage and power between genotyping platforms. Here, we quantify these gains in power and coverage by using 1,376 population controls that are from the 1958 British Birth Cohort and were genotyped by the Wellcome Trust Case-Control Consortium with the Illumina HumanHap 550 and Affymetrix SNP Array 5.0 platforms. Approximately 50% of genotypes at single-nucleotide polymorphisms (SNPs) exclusively on the HumanHap 550 c...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Evaluating the effects of imputation on the power, coverage, and cost efficiency of genome-wide SNP platforms.
Views and Downloads
If you are the owner of this record, you can report an update to it here: Report update to this record