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A prospective study of diffusion-weighted magnetic resonance imaging as an early prognostic biomarker in chemoradiotherapy in squamous cell carcinomas of the anus

Abstract:

Aims

The use of diffusion-weighted magnetic resonance imaging (DW-MRI) as a prognostic marker of treatment response would enable early individualisation of treatment. We aimed to quantify the changes in mean apparent diffusion coefficient (ΔADC_mean) between a DW-MRI at diagnosis and on fraction 8–10 of chemoradiotherapy (CRT) as a biomarker for cellularity, and correlate these with anal squamous cell carcinoma recurrence.

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.clon.2020.09.003

Authors


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Institution:
University of Oxford
Division:
MSD
Role:
Author
Publisher:
Elsevier
Journal:
Clinical Oncology More from this journal
Volume:
32
Issue:
12
Pages:
874-883
Publication date:
2020-10-03
Acceptance date:
2020-07-22
DOI:
EISSN:
1433-2981
ISSN:
0936-6555
Pmid:
33023818
Language:
English
Keywords:
Pubs id:
1136567
Local pid:
pubs:1136567
Deposit date:
2021-01-15

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