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Thesis

Design, synthesis and application of novel light-activated molecular probes

Abstract:

Caged compounds are biologically active molecules that are rendered inert by masking an important functionality with a photolabile protecting, ‘caging’, group. The caging group can be removed by irradiation with light to reveal the active compound with restored pharmacological activity with high spatial and temporal control. This technology provides an ideal tool for the study of many chemical, physiological and biological systems.

This DPhil dissertation highlights several projects ...

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Chemistry Research Laboratory
Oxford college:
St Hugh's College
Role:
Author
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Division:
MPLS
Department:
Chemistry
Role:
Author

Contributors

Division:
MPLS
Department:
Chemistry
Role:
Supervisor
More from this funder
Name:
Leverhulme Trust
Funding agency for:
Stanton-Humphreys, M
Publication date:
2010
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:1d0905c4-7fba-4796-92a5-848715204950
Local pid:
ora:5293
Deposit date:
2011-04-21

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