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A simulation study of the reliability of recombination detection methods.

Abstract:

There exist many methods to detect recombination or mosaic structure in a sample of DNA sequences. But how reliable are they? Four methods were investigated with respect to their power to detect recombination in simulated samples with different amounts of recombination and mutation. In addition, we investigated the impact of the shape of the underlying genealogy on their performances. We found that the methods detected far fewer recombinations than were theoretically possible and that methods...

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Publication status:
Published

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Journal:
Molecular biology and evolution More from this journal
Volume:
18
Issue:
10
Pages:
1929-1939
Publication date:
2001-10-01
DOI:
EISSN:
1537-1719
ISSN:
0737-4038
Language:
English
Keywords:
Pubs id:
pubs:102840
UUID:
uuid:1cff1f23-ab08-4ce1-8e4c-354aec58ec70
Local pid:
pubs:102840
Source identifiers:
102840
Deposit date:
2012-12-19

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