Journal article icon

Journal article

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.

Abstract:

The pubertal height growth spurt is a distinctive feature of childhood growth reflecting both the central onset of puberty and local growth factors. Although little is known about the underlying genetics, growth variability during puberty correlates with adult risks for hormone-dependent cancer and adverse cardiometabolic health. The only gene so far associated with pubertal height growth, LIN28B, pleiotropically influences childhood growth, puberty and cancer progression, pointing to shared ...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1093/hmg/ddt104

Authors


Cousminer, DL More by this author
Timpson, NJ More by this author
Thiering, E More by this author
Expand authors...
Journal:
Human molecular genetics
Volume:
22
Issue:
13
Pages:
2735-2747
Publication date:
2013-07-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:1ce798eb-5095-4269-94e0-61c85c14aef8
Source identifiers:
387232
Local pid:
pubs:387232

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP