Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.

Cousminer, DL; Berry, DJ; Timpson, NJ; Ang, W; Thiering, E; Byrne, EM; Taal, HR; Huikari, V; Bradfield, JP; Kerkhof, M; Groen-Blokhuis, MM; Kreiner-Møller, E; Marinelli, M; Holst, C; Leinonen, JT; Perry, JR; Surakka, I; Pietiläinen, O; Kettunen, J; Anttila, V; Kaakinen, M; Sovio, U; Pouta, A; Das, S; Lagou, V; Power, C; Prokopenko, I; Evans, DM; Kemp, JP; St Pourcain, B; Ring, S; Palotie, A; Kajantie, E; Osmond, C; Lehtimäki, T; Viikari, JS; Kähönen, M; Warrington, NM; Lye, SJ; Palmer, LJ; Tiesler, CM; Flexeder, C; Montgomery, GW; Medland, SE; Hofman, A; Hakonarson, H; Guxens, M; Bartels, M; Salomaa, V; Murabito, JM; Kaprio, J; Sørensen, TI; Ballester, F; Bisgaard, H; Boomsma, DI; Koppelman, GH; Grant, SF; Jaddoe, VW; Martin, NG; Heinrich, J; Pennell, CE; Raitakari, OT; Eriksson, JG; Smith, GD; Hyppönen, E; Järvelin, MR; McCarthy, MI; Ripatti, S; Widén, E

Abstract:

The pubertal height growth spurt is a distinctive feature of childhood growth reflecting both the central onset of puberty and local growth factors. Although little is known about the underlying genetics, growth variability during puberty correlates with adult risks for hormone-dependent cancer and adverse cardiometabolic health. The only gene so far associated with pubertal height growth, LIN28B, pleiotropically influences childhood growth, puberty and cancer progression, pointing to shared ...

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APA Style

Cousminer, D. L., Berry, D. J., Timpson, N. J., Ang, W., Thiering, E., Byrne, E. M., Taal, H. R., Huikari, V., Bradfield, J. P., Kerkhof, M., Groen-Blokhuis, M. M., Kreiner-Møller, E., Marinelli, M., Holst, C., Leinonen, J. T., Perry, J. R., Surakka, I., Pietiläinen, O., Kettunen, J., … Widén, E. (2013). Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. Human Molecular Genetics, 22(13), 2735–2747.

MLA Style

Cousminer, D. L., et al. “Genome-Wide Association and Longitudinal Analyses Reveal Genetic Loci Linking Pubertal Height Growth, Pubertal Timing and Childhood Adiposity.” Human Molecular Genetics, vol. 22, no. 13, Human molecular genetics, 2013, pp. 2735–47.

Chicago Style

Cousminer, DL, DJ Berry, NJ Timpson, W Ang, E Thiering, EM Byrne, HR Taal, et al. 2013. “Genome-Wide Association and Longitudinal Analyses Reveal Genetic Loci Linking Pubertal Height Growth, Pubertal Timing and Childhood Adiposity.” Human Molecular Genetics 22 (13): 2735–47.
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