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Journal article : Review

Non-coding RNAs set the stage for RNA polymerase II transcription

Abstract:

Effective synthesis of mammalian messenger (m)RNAs depends on many factors that together direct RNA polymerase II (pol II) through the different stages of the transcription cycle and ensure efficient cotranscriptional processing of mRNAs. In addition to the many proteins involved in transcription initiation, elongation, and termination, several noncoding (nc)RNAs also function as global transcriptional regulators. Understanding the mode of action of these non-protein regulators has been an in...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.tig.2020.09.013

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
ORCID:
0000-0001-5276-9645
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Name:
Wellcome Trust
Grant:
210641/Z/18/Z
Publisher:
Cell Press
Journal:
Trends in Genetics More from this journal
Volume:
37
Issue:
3
Pages:
279-291
Publication date:
2020-10-09
Acceptance date:
2020-09-14
DOI:
EISSN:
1362-4555
ISSN:
0168-9525
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1133240
Local pid:
pubs:1133240
Deposit date:
2020-09-22

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