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The pathology of multiple sclerosis and related disorders

Abstract:

The histopathology of multiple sclerosis (MS), the most common demyelinating disorder, is the main focus of this review. MS is characterized by inflammatory demyelination, accompanied by gliosis. The MS plaque can show ongoing active demyelination, which can be accompanied by varying degrees of remyelination, or be quiescent. The current concept that MS is an autoimmune disease of myelin has been challenged by recent studies, and it is becoming increasingly clear that neurodegeneration is a s...

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Publisher copy:
10.1016/j.mpdhp.2011.02.001

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Diagnostic Histopathology More from this journal
Volume:
17
Issue:
5
Pages:
225-231
Publication date:
2011-05-01
DOI:
ISSN:
1756-2317
Language:
English
Keywords:
Pubs id:
pubs:243918
UUID:
uuid:1cac1f12-f6d3-49ce-b762-5a5ebb6ec136
Local pid:
pubs:243918
Source identifiers:
243918
Deposit date:
2013-02-20

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