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Journal article

Synthesis and characterisation of 5-acyl-6,7-dihydrothieno[3,2-c]pyridine inhibitors of Hedgehog acyltransferase

Abstract:

In this data article we describe synthetic and characterisation data for four members of the 5-acyl-6,7-dihydrothieno[3,2-c]pyridine (termed "RU-SKI") class of inhibitors of Hedgehog acyltransferase, including associated NMR spectra for final compounds. RU-SKI compounds were selected for synthesis based on their published high potencies against the enzyme target. RU-SKI 41 (9a), RU-SKI 43 (9b), RU-SKI 101 (9c), and RU-SKI 201 (9d) were profiled for activity in the related article "Click chemi...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.dib.2016.02.012

Authors


Lanyon-Hogg, T More by this author
Masumoto, N More by this author
Konitsiotis, AD More by this author
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Publisher:
Elsevier B.V. Publisher's website
Journal:
Data in Brief Journal website
Volume:
7
Pages:
257-281
Publication date:
2016-02-10
Acceptance date:
2016-02-02
DOI:
EISSN:
2352-3409
ISSN:
2352-3409
URN:
uuid:1c98fc37-c1ca-4352-b1b0-3c310c095953
Source identifiers:
615189
Local pid:
pubs:615189

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