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Journal article

Resting CD4+ effector memory T cells are precursors of bystander-activated effectors: a surrogate model of rheumatoid arthritis synovial T-cell function.

Abstract:

BACKGROUND: Previously we described a system whereby human peripheral blood T cells stimulated for 8 days in a cytokine cocktail acquired effector function for contact-dependent induction of proinflammatory cytokines from monocytes. We termed these cells cytokine-activated (Tck) cells and found that the signalling pathways elicited in the responding monocytes were identical whether they were placed in contact with Tck cells or with T cells isolated from rheumatoid arthritis (RA) synovial tis...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/ar2390

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Name:
Arthritis Research Campaign
Publisher:
BioMed Central
Journal:
Arthritis Research and Therapy More from this journal
Volume:
10
Issue:
2
Article number:
R36
Publication date:
2008-01-01
DOI:
EISSN:
1478-6362
ISSN:
1478-6354
Language:
English
Keywords:
UUID:
uuid:1c9314ac-7090-403b-a3c9-77f9697cc76c
Local pid:
pubs:224461
Source identifiers:
224461
Deposit date:
2012-12-19

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