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Detection of polyfunctional Mycobacterium tuberculosis-specific T cells and association with viral load in HIV-1-infected persons.

Abstract:

BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) epidemic is associated with a significant increase in the incidence of tuberculosis (TB); however, little is known about the quality of Mycobacterium tuberculosis (MTB)-specific cellular immune responses in coinfected individuals. METHODS: A total of 137 HIV-1-positive individuals in Durban, South Africa, were screened with the use of overlapping peptides spanning Ag85A, culture filtrate protein 10 (CFP-10), early secretory antigen ...

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Publication status:
Published

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Publisher copy:
10.1086/529048

Authors


Mkhwanazi, N More by this author
van der Stok, M More by this author
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Volume:
197
Issue:
7
Pages:
990-999
Publication date:
2008-04-05
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
URN:
uuid:1c89a8bd-1870-409c-8120-38cd07c64184
Source identifiers:
15491
Local pid:
pubs:15491

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