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Journal article

A glimpse into the epigenetic landscape of gene regulation.

Abstract:

Post-translational modifications to histone proteins and methylation of DNA comprise the epigenome of a cell. The epigenome, which changes through development, controls access to our genes. Recent advances in DNA sequencing technology has led to genome-wide distribution data for a limited number of histone modifications in mammalian stem cells and some differentiated lineages. These studies reveal predictive correlations between histone modifications, different classes of gene and chromosomal...

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Publication status:
Published

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Publisher copy:
10.1016/j.gde.2007.12.005

Authors


Journal:
Current opinion in genetics and development
Volume:
18
Issue:
2
Pages:
116-122
Publication date:
2008-04-01
DOI:
EISSN:
1879-0380
ISSN:
0959-437X
Source identifiers:
101207
Language:
English
Keywords:
Pubs id:
pubs:101207
UUID:
uuid:1c815117-abe9-4900-84c0-a27852683661
Local pid:
pubs:101207
Deposit date:
2012-12-19

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