Journal article
Kv1.3 controls mitochondrial dynamics during cell cycle progression
- Abstract:
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The voltage-gated potassium channel Kv1.3 is a potential therapeutic target for obesity and diabetes. The genetic ablation and pharmacological inhibition of Kv1.3 lead to a lean phenotype in rodents. The mechanism of regulation of body weight and energy homeostasis involves Kv1.3 expression in different organs, including white and brown adipose tissues. Here, we show that Kv1.3 promotes the proliferation of preadipocytes through the control of mitochondrial dynamics. Kv1.3 is expressed in mit...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, 3.4MB)
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- Publisher copy:
- 10.3390/cancers13174457
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Authors
Bibliographic Details
- Publisher:
- MDPI Publisher's website
- Journal:
- Cancers Journal website
- Volume:
- 13
- Issue:
- 17
- Pages:
- 4457-4457
- Publication date:
- 2021-09-04
- Acceptance date:
- 2021-09-03
- DOI:
- EISSN:
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2072-6694
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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1196604
- Local pid:
- pubs:1196604
- Deposit date:
- 2021-09-29
Terms of use
- Copyright holder:
- Capera et al.
- Copyright date:
- 2021
- Rights statement:
- Copyright © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
- Licence:
- CC Attribution (CC BY)
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