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Intramembrane proteolysis controls diverse signalling pathways throughout evolution.

Abstract:
Regulated intramembrane proteolysis (RIP) has recently emerged as a conserved mechanism for controlling many signalling pathways in both prokaryotes and eukaryotes. Although early examples were confined to the activation of membrane-tethered transcription factors in the cell receiving the signal, recent analysis indicates that RIP also regulates the emission of factors involved in intercellular communication.
Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
Current opinion in genetics and development More from this journal
Volume:
12
Issue:
5
Pages:
512-518
Publication date:
2002-10-01
DOI:
EISSN:
1879-0380
ISSN:
0959-437X
Language:
English
Keywords:
Pubs id:
pubs:356082
UUID:
uuid:1c4be82e-4605-4e3d-a087-8c304ced065c
Local pid:
pubs:356082
Source identifiers:
356082
Deposit date:
2013-11-16

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