Malaria in malaria-naïve adults is associated with an inflammatory response characterised by expression of specific activation markers on innate immune cells. Here we investigate activation and adhesion marker expression, and cytokine production in monocytes from children presenting with cerebral malaria (CM, n=36), severe malarial anaemia (SMA, n=42) or uncomplicated malaria (UM, n= 66), and healthy aparasitemic children (n=52) in Blantyre, Malawi. In all malaria groups, but particularly in ...Expand abstract
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- Mandala et al.
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© 2016 The Authors. Parasite Immunology. Published by John Wiley and Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License,
which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Monocyte activation and cytokine production in Malawian children presenting with P. falciparum malaria
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