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Whole genome sequencing and de novo assembly identifies Sydney-like variant noroviruses and recombinants during the winter 2012/2013 outbreak in England

Abstract:

Background: Norovirus is the commonest cause of epidemic gastroenteritis among people of all ages. Outbreaks frequently occur in hospitals and the community, costing the UK an estimated £110 m per annum. An evolutionary explanation for periodic increases in norovirus cases, despite some host-specific post immunity is currently limited to the identification of obvious recombinants. Our understanding could be significantly enhanced by full length genome s...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1186/1743-422x-10-335

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Subgroup:
NDM Experimental Medicine
Oxford college:
New College
Role:
Author
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087646/Z/08/Z/Wellcome Trust More from this funder
090532/Z/09/Z/Wellcome Trust More from this funder
486/Department of Health More from this funder
G0800778/Department of Health More from this funder
Biotechnology and Biological Sciences Research Council More from this funder
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Publisher:
BioMed Central Publisher's website
Journal:
Virology Journal Journal website
Volume:
10
Issue:
1
Pages:
335
Publication date:
2013-11-13
Acceptance date:
2013-11-11
DOI:
EISSN:
1743-422X
Pubs id:
pubs:443072
URN:
uri:1c3dfe9c-bc2a-4dfc-a5bc-b743320f5e23
UUID:
uuid:1c3dfe9c-bc2a-4dfc-a5bc-b743320f5e23
Local pid:
pubs:443072

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