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Journal article

T-independent activation of B cells by vesicular stomatitis virus: no evidence for the need of a second signal.

Abstract:

Vesicular stomatitis virus (VSV) induces a T helper cell-independent IgM antibody response, whereas the IgG response is strictly T helper cell dependent. Since VSV induces B cells in complete absence of T helper cells, the question arises as to whether this induction occurs in the absence of a second signal or whether it depends upon an alternative or replacing signal 2. We therefore asked whether VSV has polyclonal B cell stimulator activity and/or whether B cell induction by VSV needs costi...

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Publication status:
Published

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Publisher copy:
10.1006/cimm.1996.0065

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Journal:
Cellular immunology
Volume:
168
Issue:
2
Pages:
184-192
Publication date:
1996-03-01
DOI:
EISSN:
1090-2163
ISSN:
0008-8749
Source identifiers:
469176

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