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Aged Tg2576 mice are impaired on social memory and open field habituation tests.

Abstract:

In a previous publication [Deacon RMJ, Cholerton LL, Talbot K, Nair-Roberts RG, Sanderson DJ, Romberg C, et al. Age-dependent and -independent behavioral deficits in Tg2576 mice. Behav Brain Res 2008;189:126-38] we found that very few cognitive tests were suitable for demonstrating deficits in Tg2576 mice, an amyloid over-expression model of Alzheimer's disease, even at 23 months of age. However, in a retrospective analysis of a separate project on these mice, tests of social memory and open ...

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Publication status:
Published

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Publisher copy:
10.1016/j.bbr.2008.09.042

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
Journal:
Behavioural brain research
Volume:
197
Issue:
2
Pages:
466-468
Publication date:
2009-02-05
DOI:
EISSN:
1872-7549
ISSN:
0166-4328
URN:
uuid:1c17a91e-971c-4515-92d1-cecad46bfcb1
Source identifiers:
18744
Local pid:
pubs:18744

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