Thesis icon

Thesis

Evaluation of a potential vaccine against hyperinvasive serogroup B Neisseria meningitidis by assessment of the effects of surface-expressed Opacity-associated proteins on the immune system

Abstract:

Neisseria meningitidis causes 500,000 cases of meningitis and septicaemia annually worldwide, with a mortality rate of approximately 10%. Most disease in developed countries is caused by serogroup B infection, against which there is no universal vaccine. Opa proteins are major meningococcal outer membrane proteins, and a limited number of Opa variants have been associated with hyperinvasive serogroup B meningococci, suggesting their use as a potential novel vaccine. Immunisation o...

Expand abstract

Actions


Access Document


Files:

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Research group:
Oxford Vaccine Group
Oxford college:
Linacre College
Role:
Author

Contributors

Division:
MSD
Department:
Paediatrics
Role:
Supervisor
More from this funder
Funding agency for:
Sadarangani, M
Grant:
RTF1263
Publication date:
2011
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:1c137f32-a37d-4cd4-bac0-4c0a927564bd
Local pid:
ora:6788
Deposit date:
2013-03-27

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP