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Rearrangement of atrial bundle architecture and consequent changes in anisotropy of conduction constitute the 3-dimensional substrate for atrial fibrillation.

Abstract:

BACKGROUND: Anisotropy of conduction facilitates re-entry and is, therefore, a key determinant of the stability of atrial fibrillation (AF). Little is known about the effect of AF on atrial bundle architecture and consequent changes in anisotropy of conduction and maintenance of AF. METHODS AND RESULTS: Direct contact mapping was performed in left atria of goats with acute AF (n=6) or persistent AF (n=5). The degree and direction of anisotropic conduction were analyzed. Mapped tissue regions ...

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Publication status:
Published

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Publisher copy:
10.1161/circep.113.000050

Authors


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Volume:
6
Issue:
5
Pages:
967-975
Host title:
Circulation. Arrhythmia and electrophysiology
Publication date:
2013-10-01
Event location:
United States
DOI:
EISSN:
1941-3084
ISSN:
1941-3149
Source identifiers:
364222
Keywords:
Pubs id:
pubs:364222
UUID:
uuid:1c12d4c8-5cdf-43b6-8cbd-d11e07296a7c
Local pid:
pubs:364222
Deposit date:
2013-11-17

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