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Isolation of candidate cDNAs for portions of the Duchenne muscular dystrophy gene.

Abstract:

Duchenne muscular dystrophy (DMD) and the less severe Becker muscular dystrophy (BMD) are human X-linked muscle-wasting disorders that have been localized to the band Xp21 by genetic linkage analysis and cytologically detectable abnormalities. A cloned DNA segment, DXS164 (or pERT87), has been shown to detect deletions in the DNA of unrelated DMD and BMD males. Here we present the nucleotide sequence of two highly conserved DNA fragments from the DXS164 locus and their homologous sequences fr...

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Publication status:
Published

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Publisher copy:
10.1038/323646a0

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Role:
Author
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Journal:
Nature
Volume:
323
Issue:
6089
Pages:
646-650
Publication date:
1986-01-01
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:1be817d0-f9c3-4fc7-a178-324ac8a5cdb6
Source identifiers:
115667
Local pid:
pubs:115667

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