Journal article icon

Journal article

Reward sensitivity and action in Parkinson’s disease patients with and without apathy

Abstract:

Clinical apathy results in dysfunction of goal directed behaviour, a key component of which is the initiation of action. Previous work has suggested that blunting of reward sensitivity is an important mechanism underlying apathy. However, an additional component might be impoverished initiation of action itself. This study aims to investigate the link between motivation and motor output and its association with apathy and dopamine. An oculomotor task that measures pupillary and saccadic respo...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1093/braincomms/fcab022

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Oxford college:
New College
Role:
Author
ORCID:
0000-0001-5192-4375
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
ORCID:
0000-0003-0735-4349
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Oxford college:
New College
Role:
Author
ORCID:
0000-0002-6850-9255
More from this funder
Name:
Wellcome Trust
Grant:
104364/Z/14/Z
More from this funder
Name:
National Institute for Health Research
Grant:
CL-2018-13-006
More from this funder
Name:
Wellcome Trust Clinical Research Training Fellowship and a National Institute for Health Research Clinical Lectureship
Publisher:
Oxford University Press
Journal:
Brain Communications More from this journal
Volume:
3
Issue:
2
Place of publication:
England
Publication date:
2021-03-10
Acceptance date:
2021-01-04
DOI:
EISSN:
2632-1297
Pmid:
33855297
Language:
English
Keywords:
Pubs id:
1168212
Local pid:
pubs:1168212
Deposit date:
2021-12-02

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP