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Intra-individual reaction time variability in amnestic mild cognitive impairment: a precursor to dementia?

Abstract:

We used an exogenous target detection cueing paradigm to examine whether intra-individual reaction time variability (IIV) or phasic alerting varied significantly between patients with amnestic mild cognitive impairment (aMCI) (n = 45) and healthy older adult controls (n = 31) or between those with aMCI who, within a 2.5 year follow-up period, developed dementia (n = 13) and those who did not (n = 26). Neither IIV, nor simple reaction time, differentiated aMCI from healthy aging, indicating th...

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Publication status:
Published

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Publisher copy:
10.3233/jad-2012-120505

Authors


Leonards, U More by this author
Snowden, RJ More by this author
Philips, M More by this author
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Journal:
Journal of Alzheimer's disease : JAD
Volume:
32
Issue:
2
Pages:
457-466
Publication date:
2012
DOI:
EISSN:
1875-8908
ISSN:
1387-2877
URN:
uuid:1bdf4b6e-4998-40d8-9244-c6fec197e3db
Source identifiers:
356628
Local pid:
pubs:356628

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