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Journal article

Cellular diversity in the Drosophila midbrain revealed by single-cell transcriptomics

Abstract:

To understand the brain, molecular details need to be overlaid onto neural wiring diagrams so that synaptic mode, neuromodulation and critical signaling operations can be considered. Single-cell transcriptomics provide a unique opportunity to collect this information. Here we present an initial analysis of thousands of individual cells from Drosophila midbrain, that were acquired using Drop-Seq. A number of approaches permitted the assignment of transcriptional profiles to several major brain...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.7554/elife.34550

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
ORCID:
0000-0002-6994-091X
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology Anatomy and Genetics
Role:
Author
ORCID:
0000-0003-4503-6229
More from this funder
Name:
Fondation Bettencourt Schueller
Funding agency for:
Waddell, S
Grant:
200846/Z/16/Z
More from this funder
Name:
Wellcome Trust
Funding agency for:
Croset, V
Treiber, C
Waddell, S
Grant:
200846/Z/16/Z
Publisher:
eLife Sciences Publications
Journal:
eLife More from this journal
Volume:
7
Article number:
e34550
Publication date:
2018-04-30
Acceptance date:
2018-04-18
DOI:
ISSN:
2050-084X
Pmid:
29671739
Language:
English
Keywords:
Pubs id:
pubs:843489
UUID:
uuid:1bbeb89e-28c0-4f1a-81bf-1dde47f604c7
Local pid:
pubs:843489
Deposit date:
2018-05-01

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