- Abstract:
-
Symptomatic dengue virus (DENV) infections range from mild fever to severe haemorrhagic disease and death. Host-viral interactions play a significant role in deciding the fate of the infection. The unfolded protein response (UPR) is a pro-survival cellular reaction induced in response to DENV mediated ER stress. The UPR has complex interactions with the cellular autophagy machinery, apoptosis and innate immunity. DENV has evolved to manipulate the UPR to facilitate its replication and to evad...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted manuscript
- Files:
-
-
(pdf, 2.5mb)
-
- Publisher copy:
- 10.1111/cmi.12734
-
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- Publisher:
- Wiley Publisher's website
- Journal:
- Cellular Microbiology Journal website
- Volume:
- 19
- Issue:
- 5
- Pages:
- e12734
- Publication date:
- 2017-03-05
- Acceptance date:
- 2017-02-15
- DOI:
- EISSN:
-
1462-5822
- ISSN:
-
1462-5814
- Pubs id:
-
pubs:680085
- URN:
-
uri:1bb812fb-8491-4eed-bc10-9d5c6ba3ff17
- UUID:
-
uuid:1bb812fb-8491-4eed-bc10-9d5c6ba3ff17
- Local pid:
- pubs:680085
- Keywords:
- Copyright holder:
- John Wiley and Sons Ltd
- Copyright date:
- 2017
- Notes:
- © 2017 John Wiley and Sons Ltd
Journal article
The role of the unfolded protein response in dengue virus pathogenesis
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