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Journal article

Novel genetic loci underlying human intracranial volume identified through genome-wide association.

Abstract:

Intracranial volume reflects the maximally attained brain size during development, and remains stable with loss of tissue in late life. It is highly heritable, but the underlying genes remain largely undetermined. In a genome-wide association study of 32,438 adults, we discovered five previously unknown loci for intracranial volume and confirmed two known signals. Four of the loci were also associated with adult human stature, but these remained associated with intracranial volume after adjus...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/nn.4398

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
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Name:
National Institutes of Health
Grant:
U54 EB020403
Publisher:
Nature Publishing Group
Journal:
Nature Neuroscience More from this journal
Volume:
19
Issue:
12
Pages:
1569-1582
Publication date:
2016-10-01
Acceptance date:
2016-08-31
DOI:
ISSN:
1097-6256 and 1546-1726
Pmid:
27694991
Language:
English
Keywords:
Pubs id:
pubs:648308
UUID:
uuid:1baccce9-2efc-45d2-bb9b-f1bb7ded5254
Local pid:
pubs:648308
Source identifiers:
648308
Deposit date:
2017-05-04

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