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Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics

Abstract:

Background:Quantitative molecular data from urine are rare in epidemiology and genetics. NMR spectroscopy could provide these data in high throughput, and it has already been applied in epidemiological settings to analyse urine samples. However, quantitative protocols for large-scale applications are not available. Methods:We describe in detail how to prepare urine samples and perform NMR experiments to obtain quantitative metabolic information. Semi-automated quantitative line shape fitting ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/ije/dyy287

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Publisher:
Oxford University Press Publisher's website
Journal:
International Journal of Epidemiology Journal website
Volume:
48
Issue:
3
Pages:
978-993
Publication date:
2019-01-25
Acceptance date:
2018-12-08
DOI:
EISSN:
1464-3685
ISSN:
0300-5771
Pmid:
30689875
Source identifiers:
967037
Language:
English
Keywords:
Pubs id:
pubs:967037
UUID:
uuid:1b95085c-0ef6-4e10-8635-0daf615286ea
Local pid:
pubs:967037
Deposit date:
2019-02-27

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