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Thesis

The role of Galectin-3 in the subventricular zone response to demyelination

Abstract:

Multiple sclerosis (MS) is a debilitating neurological condition that causes demyelination and axon degeneration. While relapsing forms of the disease have been treatable for many years, progressive forms lack definitive treatment. An hypothesised therapy involves neural stem cells repairing and replacing damaged oligodendrocytes and neurons. The subventricular zone (SVZ) is a known site of adult neurogenesis and is adjacent to the corpus callosum (CC) white matter region. Previous studies...

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Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author

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Supervisor
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Name:
James Fairfax - Oxford Australia Scholarship Fund
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:1b36c71f-c148-45b8-99c7-00f60d35215b
Deposit date:
2016-09-19

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