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Development of a repository of individual participant data from randomized controlled trials of therapists delivered interventions for low back pain

Abstract:
Background: Individual patient data (IPD) meta-analysis of existing randomized controlled trials (RCTs) is a promising approach to achieving sufficient statistical power to identify sub-groups. We created a repository of IPD from multiple low back pain (LBP) RCTs to facilitate a study of treatment moderators. Due to sparse heterogeneous data, the repository needed to be robust and flexible to accommodate millions of data points prior to any subsequent analysis. Metho... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/ejp.984

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
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Name:
National Institute for Health Research
Grant:
Applied Research Programme (Grant Reference Number RP-PG-0608- 10076
Publisher:
John Wiley & Sons Ltd
Journal:
European Journal of Pain More from this journal
Volume:
21
Issue:
5
Pages:
815–826
Publication date:
2016-01-01
Acceptance date:
2016-11-02
DOI:
EISSN:
1532-2149
ISSN:
1090-3801
Pubs id:
pubs:666595
UUID:
uuid:1a9e4227-82f4-4bf5-b4d2-a9693d1dcd9b
Local pid:
pubs:666595
Source identifiers:
666595
Deposit date:
2016-12-19

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